Development of a curative therapy in aggressive leukaemia

    NAME Dr Jenny Y. Wang
    CANCER TYPE Leukaemia
    INSTITUTION University of New South Wales, CCI
    STATE New South Wales
    GRANT TYPE $200,000
    PROJECT TYPE Research

    Targeting self-renewal pathways for the development of a curative therapy in aggressive leukaemia

    "In this study, we will validate a recently-developed therapeutic antibody that specifically targets the R-spondin pathway critical for Leukaemia stem cells survival. This preclinical evidence is essential for drug testing that will enable the development of future clinical studies for the treatment of leukaemia with poor prognosis and to improve the dismal outcome of acute myeloid leukaemia."
    - University of New South Wales, Children's Cancer Institute