? Exploiting defective DNA repair pathways

NAME Dr. Chuck Bailey
CANCER TYPE Endometrial
INSTITUTION Centenary Institute
STATE New South Wales
GRANT TYPE $50,000

Exploiting defective DNA repair pathways as a novel therapeutic target in endometrial cancer

"We will use molecular genetic and cell biology techniques to confirm the DNA damage response in CTCF-mutant endometrial cancer cell lines. We will examine the sensitivity of endometrial cancer cell lines to PARP inhibition and then test whether combination therapies are effective in CTCF-mutant endometrial cancer. This may lead to improved molecular treatments for endometrial cancer."

Dr Chuck Bailey, Centenary Institute

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