Repurposing of the arthritis drug Tofacitinib to treat metastatic breast cancer

"We have identified a unique mechanism of resistance which could be therapeutically targeted in patients. In this project we will use our pre-clinical disease models to identify which proteins are being changed in resistance and to test this new therapy (Tofacitinib). The major benefits will be improved diagnosis, new treatment and increased survival."

- Garvan Institute of Medical Research