NAME Dr Benjamin Heng
CANCER TYPE Breast cancer
INSTITUTION Macquarie University
STATE New South Wales
GRANT TYPE Other
PROJECT TYPE Research

Macquarie University: “Re-educating” immune cells as a combination therapy to limit breast cancer metastasis. Tumours alter biochemical pathways to reduce immune response and so spread (metastasise). One such pathway is the kynurenine pathway (KP), which is elevated in patients with invasive breast cancer. This proposal will examine if inhibition of the KP will provide an effective therapy to limit metastasis and/or relapse.