NAME Dr Charles Bailey
CANCER TYPE Leukaemia
INSTITUTION Centenary Institute Of Cancer Medicine and Cell Biology
STATE New South Wales
GRANT TYPE $200,000
PROJECT TYPE Research

Genetic Disruption of CTCF-mediated Protein complexes in Leukaemia Mutations in the genome-organising protein CTFC and its co-factors commonly occur in 40% of acute lymphoblastic leukaemia (ALL) patients. In the genetic screen in mice they will reveal whether disruption of CTFC-medicated complexes is a critical event in ALL and reveal new therapeutic targets.