Repurposing of the arthritis drug Tofacitinib to treat metastatic breast cancer

    NAME Dr Liz Caldon
    CANCER TYPE Breast cancer
    INSTITUTION Garvan Institute of Medical Research
    STATE New South Wales
    GRANT TYPE $50,000
    PROJECT TYPE Research

    Repurposing of the arthritis drug Tofacitinib to treat metastatic breast cancer

    "We have identified a unique mechanism of resistance which could be therapeutically targeted in patients. In this project we will use our pre-clinical disease models to identify which proteins are being changed in resistance and to test this new therapy (Tofacitinib). The major benefits will be improved diagnosis, new treatment and increased survival."

    - Garvan Institute of Medical Research